Exam Preview for 34189: Role of DNA Repair in the Cochlea, presente

Role of DNA Repair in the Cochlea, presented in partnership with the American Auditory Society

Please note: exam questions are subject to change.

1. What causes DNA damage in the cochlea? Endolymphatic hydrops Sudden sensorineural hearing loss Noise over-exposure Binaural release from masking
2. Which endogenous stressor can damage DNA? Normal cellular metabolism Sun exposure Over-cooked foods Alcohol
3. Which exogenous stressor can damage DNA? Low cholesterol Low blood flow Inflammation Some types of medication
4. Human mutations in DNA repair genes result in? Dead hair cells Increased difference limen for frequency Hyperactive stria vascularis Increased endolymphatic potential
5. How does spiral ganglion neurons respond to DNA damage? They release acetylcholine They are flooded with perilymph They multiply They relocate DNA repair proteins
6. How can cochlear DNA be protected? By cochlear DNA repair enzymes By persistent noise exposure By impulse noise By loop diuretics
7. Identify a functional consequence of protecting cochlear DNA? Improved cognitive functions Reduced depression Preservation of cochlear sensitivity Reduced anxiety
8. Which tissues or cells in the cochlea have DNA repair enzymes? Cortilymph Endolymph Perilymph Stria vascularis
9. How do hair cells respond to DNA damage? They translocate repair proteins into their nucleus They are poor at responding to DNA damage They cannot produce repair proteins They never develop DNA damage
10. Improving cochlear DNA repair could limit? Meniere's disease Central auditory processing disorders Noise induced hearing loss Middle ear infections