This course will summarize current research efforts focusing on gene manipulation, gene therapy and stem cell transplantation for repairing or replacing damaged mammalian cochlear hair cells. The presentation will emphasize how these approaches might be used therapeutically. Finally, the presentation will review how this research applies to clinical audiology and what role the audiologist will play in future biochemical and pharmacological approaches to hearing restoration.
Course created on October 16, 2019
- After this course, participants will be able to describe the way in which normal development of hair cells has been used to understand possible ways to regenerate hair cells after damage in mature ears.
- After this course, participants will be able to describe the difference between stem cell and gene therapy as they are applied to regenerate or replace hair cells.
- After this course, participants will be able to describe the current state of clinical trials and the future role of audiologists in biological and pharmaceutical therapies for hearing restoration.
|0-15 Minutes||Introduction by Radhika Aravamudhan, PhD|
|15-30 Minutes||What we’ve learned from birds about hair cell regeneration strategies|
|30-40 Minutes||Stem cell therapy|
|40-60 Minutes||Gene therapy|
|60-70 Minutes||Small molecule therapy|
|70-85 Minutes||Clinical trials|
|85-90 Minutes||Summary, Q & A|
Brenda M. Ryals, PhD
Dr. Ryals is Professor Emerita in Communication Sciences and Disorders at James Madison University. Her research on the neural and functional consequences of hair cell regeneration has been funded by the NIDCD/NIH and the Dept. of Veterans Affairs since 1984. She co-authored the first paper describing the discovery of hair cell regeneration in birds. She has published over 100 scientific articles and abstracts, 8 book chapters and given more than 75 presentations in the US, Japan, Russia and Western Europe. She is a former member of the Executive Board of the American Academy of Audiology, and is currently a Board of Trustee for the American Academy of Audiology and Editor-in-Chief of the journal of Ear and Hearing.
Radhika Aravamudhan, PhD
Dr. Radhika Aravamudhan is the Dean of Salus University's Osborne College of Audiology (OCA). She is responsible for the development, implementation, assessment, and accreditation of the University’s on-campus Doctor of Audiology program, as well as the Master of Science in Clinical Audiology program and Summer Workshops within OCA in consultation with the faculty and administrators.
Radhika Aravamudhan: Financial: Radhika Aravamudhan is employed by Salus University. Non-financial: Radhika Aravamudhan has no relevant non-financial relationships to disclose.
Sponsor Disclosure: This course is presented by Salus University in partnership with AudiologyOnline.
Content Disclosure: This learning event does not focus exclusively on any specific product or service.
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American Academy of Audiology
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Australian College of Audiology
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American Speech-Language-Hearing Assn.
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British Academy of Audiology
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Canadian Academy of Audiology
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California Speech-Language Pathology & Audiology Board
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International Hearing Society
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Kansas Department for Aging and Disability Services
Kansas Department of Health and Environment: Approved for 1.5 continuing education clock hours for Kansas licensed Audiologists by the Kansas Department for Aging and Disability Services. Long-Term Sponsorship number LTS-S0035.
New Zealand Audiological Society
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Speech-Language & Audiology Canada
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