Congenital cytomegalovirus (CMV) infection is the most common congenital infection in newborns and is a leading cause of hearing loss in children. Most infants with congenital CMV are asymptomatic at birth, but at risk for developing hearing impairment. With improved diagnostic testing for congenital CMV and more widespread recognition of the importance of early identification of infants at risk for hearing loss, there is increasing interest to screen all newborn infants for congenital CMV. This presentation will review the epidemiology and outcome of congenital CMV and the testing modalities to screen newborn infants. In addition, the current movement towards more widespread targeted and universal screening for congenital CMV will be discussed.
Course created on December 11, 2019
- After this course learners will be able to describe the clinical spectrum and outcomes of congenital cytomegalovirus infection.
- After this course learners will be able to describe the appropriate diagnostic test to screen and diagnose congenital CMV in the newborn infant.
- After this course learners will be able to explain how to evaluate infant with congenital CMV and understand treatment recommendations for congenital CMV infection.
- After this course learners will be able to describe the difference between targeted and universal newborn CMV screening.
|0-15 Minutes||Incidence, symptoms and clinical presentation of CMV; Review of the most common sequelae which are hearing loss, opthamologic and cognitive impairment.|
|15-30 Minutes||Initiatives of legislative updates on CMV screening legislation comparing targeted and universal screening; Benefits and limitations of three CMV screening and diagnostic test using saliva, urine and DBS (dried blood spot); Comparison of viral loads and sensitivity and specificity of the screening methods|
|30-50 Minutes||Target vs Universal screening identification and intervention; Predictors of hearing loss in cases of symptomatic and asymptomic congential CMV; Other treatment options available including Early Intervention enrollment and follow-up audiological testing; Treatment options with Ganciclovir or Valganciclovir based on the classification of CMV – symptomic vs asymptomic with or without symptoms|
|50-60 Minutes||Elements for comprehensive evaluation and treatment for symptomatic and asymptomatic infants with CMV. Limitations of target CMV screening; Challenges of universal CMV screening and follow-up; Current research being done to monitor the impact of universal vs. target screening and the treatment options available.|
Associate Professor of Pediatrics and Microbiology
Dr. Shannon Ross is an Associate Professor of Pediatrics and Microbiology in the Division of Pediatric Infectious Diseases at the University of Alabama at Birmingham. Dr. Ross earned her medical degree from the University of Alabama School of Medicine. She completed her Pediatric residency and Pediatric Infectious Diseases fellowship at the University of Alabama at Birmingham. During her fellowship training Dr. Ross also earned an MSPH in Clinical Research at the University of Alabama School of Public Health. Dr. Ross is an active clinician and researcher, with her research focused on the natural history and pathogenesis of congenital cytomegalovirus infection, with special emphasis on translational research exploring virological and clinical markers of outcome in CMV-related hearing loss.
Sponsor Disclosure: This Course is presented by Otometrics North America, a division of Natus (formerly Audiology Systems) in partnership with AudiologyOnline.
Content Disclosure: This learning event does not focus exclusively on any specific product or service.
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